Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease.
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چکیده
منابع مشابه
Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease.
In Alzheimer disease, paired helical filaments accumulate in the neuron, and amyloid fibers are found in the extracellular space in the neuropil and brain vessels. Amyloid and paired helical filaments are morphologically distinct. Although messenger RNA that encodes the amyloid has also been shown in several tissues, including brain, the intracellular expression of the protein has not been obse...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1989
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.86.8.2853